Publications

Recent key publications

Kakava-Georgiadou N, Severens JF, Jørgensen AM, Garner KM, Luijendijk MCM, Drkelic V, van Dijk R, Pers TH, Basak O, Adan RAH. Single-cell analysis reveals cellular heterogeneity and molecular determinants of hypothalamic leptin-receptor cells. Bioarxiv. 2020. doi: 10.1101/2020.07.23.217729

Donega V, van der Geest AT, Sluijs JA, van Dijk RE, Wang CC, Basak O, Pasterkamp RJ, Hol EM. Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors. Nat Commun. 2022 Feb 24;13(1):1036. doi: 10.1038/s41467-022-28626-9. PMID: 35210419; PMCID: PMC8873234.

Donega V, Burm SM, van Strien ME, van Bodegraven EJ, Paliukhovich I, Geut H, van de Berg WDJ, Li KW, Smit AB, Basak O, Hol EM. Transcriptome and proteome profiling of neural stem cells from the human subventricular zone in Parkinson’s disease. Acta Neuropathol Commun. 2019 Jun 3;7(1):84. doi: 10.1186/s40478-019-0736-0. Erratum in: Acta Neuropathol Commun. 2019 Aug 14;7(1):131. PMID: 31159890; PMCID: PMC6545684.

Basak O, Krieger T, Muraro M, Wiebrands K, Stange DE, Aldeguer JF, Rivron RC, van de Wetering M, van Es JH, Oudenaarden A, Simons B, Clevers H. Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy. PNAS, published online Jan 8; doi: 10.1073/pnas.1715911114. PMID: 29311336

For detailed information on publications and citations: https://scholar.google.nl/citations?user=fQ4hU6UAAAAJ&hl=en

Single cell analysis of the adult mouse neural stem cells. The plots show expression of respective genes in single cells of the adult subventricular zone, a major neurogenic niche. The images are generated using single molecule fluorescent in situ hybridisation and show expression of individual mRNA molecules in the neurogenic niche (Basak et al, PNAS, 2018)
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